What is the purpose of polyhexamethylene biguanide? Do you know about PHMB? The chemical that is used in many things that you are using in your daily life is PHMB. So, let’s talk about that incredible chemical;

An antiseptic with antiviral and antibacterial qualities, polyhexamethylene biguanide (PHMB) is used in many goods, such as wound care dressings, perioperative cleaning products, contact lens solutions, and swimming pool cleaners. The properties of PHMB are unique that will surprise you. It is non-corrosive to the skin and challenging for human organs to absorb. High molecular weight polymer polyhexamethylene biguanide hydrochloride is easily washable away.

In this article, you will get all the information about the property of wound prevention at PHMB. Let’s start with its introduction!

What is Polyhexamethylene Biguanide Role in Wound Healing?

Polyhexamethylene Biguanide (PHMB) kills germs, preventing cross-contamination, restricting bacteria in the wound, and creating a healing environment on the body through the dressing. The damage is safe from germs and dust particles due to this stunning dress PHMB.

AMD antimicrobial dressings are an innovative and established infection prevention method. They include 0.2% Biguanide (PHMB), a bacteria-killing polymer. It prevents the wound from growing all kinds of bacteria, including gram-positive and gram-negative.

The PHMB dressing covers the surface of an injury and kills all sorts of bacteria to prevent the wound. Due to its excellent use, it should be present at home. Doctors use it as the ideal protector of scars because recent research shows that phmb biocide has the best antimicrobial and antibacterial activity they have ever seen.

It has the property to attack the cell wall of bacteria that destroys the bacteria cell due to the destruction of its supporting material.

PHMB similarity with AMP

The synthetic polymer PHMB, an antiseptic molecule, shares structural similarities with naturally occurring antimicrobial peptides. This similarity shows that PHMB is effective for wound prevention. So, it is ideal for the use in wound prevention.

Reasons of the use of PHBM

The reasons for antimicrobial and antibacterial activity

  • Here are some reasons to use it as an antibacterial and antimicrobial substance;
  • It is associated with minimal systemic absorption.
  • It is effective against likely contaminants and pathogens.
  • It is the most inexpensive material for use.
  • It cannot promote bacterial resistance; bacteria become weak and ultimately die.
  • It is non-carcinogenic and non-to host cells. Your body will be safe by using it.
  • It is easily accessible. You can purchase it from any online and local retailer.
  • It is nontoxic for the body of the user.

Structure of PHMB

Because of its structural resemblance to AMP, PHMB has the same ability to penetrate bacterial cell membranes and kill germs. However, PHMB does not affect the proteins that make up the membranes of animal cells. It is believed that PHMB causes target cell membranes to leak potassium ions and other dissolved ions from the cytoplasm once it has attached to the membranes.

Final Words

Due to its excellent properties, PHMB is used in pharmaceuticals, detergents, and skin care cosmetic products. Due to its skincare properties, people use it in many products for many purposes.


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